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SARS-CoV-2-associated ssRNAs trigger inflammation and immunity via toll-like receptors – News-Medical.Net

Severe COVID-19 causes sepsis-like manifestations, intense lung injury, and multi-organ failure, all associated with the overproduction of pro-inflammatory cytokines….

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense single-stranded (ssRNA) virus that belongs to the Coronaviridae family. It is also closely related to the Middle East respiratory syndrome coronavirus (MERS-CoV) and SARS-CoV-1. SARS-CoV-2 infection causes coronavirus disease 2019 (COVID-19) and develops into severe respiratory distress in a subgroup of patients. Severe COVID-19 causes sepsis-like manifestations, intense lung injury, and multi-organ failure, all associated…

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